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39.5: Diagrammatic representation of coronary haemodynamics.

Sdek P, Ying H, Chang DL, Qiu W, Zheng H, Touitou R, Allday MJ, Xiao ZX (2005) MDM2promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma pro-tein.

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The N-terminus is divided in three subdomains: the transactivation domains 1 and 2(TAD1 and TAD2) and the proline-rich domain (PRD); the central domain is the DNA-bindingdomain (DBD); and, the C-terminus is formed by the nuclear localization sequence (NLS), theoligomerization domain (OD) and the regulatory domain (RD) [ 60 ]. Its metabolismis inhibited by CYP 3A4 inhibitors. Generators of somatosensory evoked potentials investigated bydipole tracing in the monkey.

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(2005) Corticonigral degeneration withneuronal achromasia and basal neurofi brillary tangles. The SORL1 gene on chromosome 11 and ahost of other candidate genes (see www.alzgene.org) alsoexplain small percentages of the variance with regard torisk for AD.
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